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Hydrogel-based strong and fast actuators by electroosmotic turgor pressure
Prof. Jeong-yun Sun & Prof. Ho-young Kim
A research team led by Sun, Jeong-Yun of the Department of Materials Science and Engineering and Kim, Ho-Young of the Department of Mechanical Engineering announced that they have developed hydrogel actuators that can produce enough strength to break bricks in a short time.
Research Highlights Board
Exploiting the full advantages of colloidal perovskite nanocrystals for large-area efficient light-e...
Prof. Tae-Woo Lee
Cost-effective, high-throughput industrial applications of metal halide perovskites in large-area displays are hampered by the fundamental difficulty of controlling the process of polycrystalline film formation from precursors, which results in the random growth of crystals, leading to non-uniform large grains and thus low electroluminescence efficiency in large-area perovskite light-emitting diodes (PeLEDs).
Spatial epitranscriptomics reveals A-to-I editome specific to cancer stem cell microniches
Prof. Sunghoon Kwon & Prof. Wonshik Ha
Epitranscriptomic features, such as single-base RNA editing, are sources of transcript diversity in cancer, but little is understood in terms of their spatial context in the tumour microenvironment.
MarcoPolo: a method to discover differentially expressed genes in single-cell RNA-seq data without d...
Prof. Buhm Han & Prof. Keehoon Jung
The standard analysis pipeline for single-cell RNA-seq data consists of sequential steps initiated by clustering the cells. An innate limitation of this pipeline is that an imperfect clustering result can irreversibly affect the succeeding steps.
Potential Impact of Late 1980s Regime Shift on the Collapse of Walleye Pollock Catch in the Western ...
Prof. Yang-Ki Cho
Walleye pollock (Gadus chalcogramma) caught in the Korean fishing area dramatically decreased in the late 1980s. To investigate the potential impact of the late 1980s climate regime shift on the collapse of the pollock catch, we developed a three-dimensional hydrodynamic model with data assimilation and a particle tracking model.
SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance ...
Prof. Jae Bum Kim
Emerging evidence indicates that the accretion of senescent cells is linked to metabolic disorders. However, the underlying mechanisms and metabolic consequences of cellular senescence in obesity remain obscure.
Ninjurin1 drives lung tumor formation and progression by potentiating Wnt/β-Catenin signaling throug...
Prof. Ho-Young Lee
Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role of Ninj1 in the context of lung tumorigenesis remains largely unknown.
In situ multiscale probing of the synthesis of a Ni-rich layered oxide cathode reveals reaction hete...
Prof. Kisuk Kang
A research team led by Kang, Kisuk and Park, Jung Won of the College of Engineering revealed a synthetic secret of high-Ni cathode materials that are attracting worldwide attention as the next-generation cathode material for lithium-ion batteries and identified the cause of low-quality synthesis.
SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell a...
Prof. Sung Joong Lee
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is accompanied by chronic neurological sequelae such as cognitive decline and mood disorder, but the underlying mechanisms have not yet been elucidated.
Comparative analysis of the oral microbiome of burning mouth syndrome patients
Prof. Gehoon Chung, Prof, Ji Woon Park, Prof. Bumjo Oh
Burning mouth syndrome (BMS) is a chronic pain condition accompanied by unpleasant burning sensations of the oral mucosa. While multiple factors were proposed for the etiology, evidence suggested a neuropathic pain origin while others suspected the use of antibiotics as the underlying cause. Interestingly, several reports demonstrated the intimate interaction of the nervous system and the microbiome.
Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via aut...
Prof. Kyung-Sun Kang
Niemann-Pick Type C disease (NPC) is a rare fatal neurodegenerative disorder caused by mutations in the NPC1 or NPC2 gene,1 leading to abnormal accumulation of non-esterified cholesterol in lysosomes.
The C. elegans Regulatory Factor X (RFX) DAF-19M module : a shift from general ciliogenesis to cell-...
Prof. Junho Lee
Cilia are important for the interaction with environments and the proper function of tissues. While the basic structure of cilia is well conserved, ciliated cells have various functions.
CPNE7 regenerates periodontal ligament via TAU-mediated alignment and cementum attachment protein-me...
Prof. Joo-Cheol Park
Once the periodontal ligament (PDL) is damaged, it is difficult to regenerate its characteristic structure. Copine7 (CPNE7) reportedly plays a functional role in supporting periodontal attachment and PDL alignment.