Research Research Highlights
Research Highlights
Research Highlights
Research Highlights
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Atomic lift-off of epitaxial membranes for cooling-free infrared detection
Prof. Celesta S. Chang
Professor Celesta S. Chang's research team from the Department of Physics and Astronomy has developed an 'Atomic Lift-Off' technique that enables the production of ultrathin, freestanding perovskite oxide membranes—paving the way for high-performance, cooling-free infrared sensors.
Research Highlights Board

Passive and active suppression of transduced noise in silicon spin qubits
Prof. Dohun Kim
Professor Dohun Kim's research team from the Department of Physics and Astronomy at SNU has successfully developed two techniques to suppress noise and its effects, which hinder high-fidelity quantum operations. Using these methods, they achieved a two-fold improvement in inhomogeneous coherence time and a ten-fold improvement in the quality of Rabi oscillations.

Professor Seung-Kyun Kang's Research Team at Seoul National University Developed the World’s Most Sensitive Flexible Strain Sensor
Prof. Seung-Kyun Kang
Seoul National University College of Engineering announced that a research team led by Prof. Seung-Kyun Kang from the Department of Materials Science and Engineering at Seoul National University (first authors: Dr. Jae-Hwan Lee and Ph.D. candidate Yoon-Nam Kim) has developed a strain sensor with record-breaking sensitivity in collaboration with researchers from Dankook University, Ajou University, and Purdue University.

Mutually antagonistic molecular clips: symmetry-breaking non-covalent bonds at the chiral–nonchiral interface
Prof. Dongwhan Lee
The homochirality of life remains an unresolved scientific question. Prevailing models postulate that homochirality arose through mutual antagonism. In this mechanism, molecules of opposite handedness deactivate each other, amplifying even a small enantiomeric excess into a larger proportion.

SNU-Hyundai Motor Group Jointly Develop Advanced Technology for Evaluating Fuel Cell Catalyst Durability and Degradation Mechanisms
Prof. Jungwon Park and Jaeyune Ryu
The College of Engineering at Seoul National University announced that Professors Jungwon Park and Jaeyune Ryu of the Department of Chemical and Biological Engineering, in collaboration with Hyundai Motor Group, have developed an innovative technology for rapid durability assessment and identification of degradation mechanisms of hydrogen fuel cell catalysts.

Compositional Optimization for Miticidal Activity, Ecotoxicity, and Phytotoxicity of Rosmarinus officinalis Essential Oils as Biorational Pesticides
Prof. Jun-Hyung Tak
The SNU CALS team, led by Prof. Jun-Hyung Tak, has presented a framework to optimize the composition of natural product-based pesticides, maximizing pesticidal activity while minimizing undesirable effects such as ecotoxicity and phytotoxicity.

Discovery of Highly Active Kynureninases for Cancer Immunotherapy through Protein Language Model
Prof. Woon Ju Song & Prof. Martin Steinegger
Overcoming the immunosuppressive tumor microenvironment is a promising strategy in anticancer therapy. L-kynurenine, a strong immunosuppressive metabolite can be degraded through kynureninases.

Discovery of Highly Active Kynureninases for Cancer Immunotherapy through Protein Language Model
Prof. Woon Ju Song and Martin Steinegger
Tailor-made enzymes empower a wide range of versatile applications, although searching for the desirable enzymes often requires high throughput screening and thus poses significant challenges. In this study, we employed homology searches and protein language models to discover and prioritize enzymes by their kinetic parameters.

Cerebellar Bergmann glia integrate noxious information and modulate nocifensive behaviors
Prof. Sang Jeong Kim
The cerebellum is activated by noxious stimuli and pathological pain but its role in noxious information processing remains unknown.

Induction of Oral Lichen Planus-Like Histopathology in Mice
Prof. Youngnim Choi
Oral lichen planus (OLP) is a chronic T cell-mediated inflammatory mucosal disease of unknown etiology. The lack of suitable animal models has hampered understanding its etiopathogenesis.

Impaired chaperone-mediated autophagy leads to abnormal SORT1 (sortilin 1) turnover and CES1-dependent triglyceride hydrolysis
Prof. Byung-Hoon Lee
SORT1 (sortilin 1), a member of the the Vps10 (vacuolar protein sorting 10) family, is involved in hepatic lipid metabolism by regulating very low-density lipoprotein (VLDL) secretion and facilitating the lysosomal degradation of CES1 (carboxylesterase 1), crucial for triglyceride (TG) breakdown in the liver.

Genome-wide phenotypic profiling of transcription factors and identification of novel targets to control the virulence of Vibrio vulnificus
Prof. Sang Ho Choi
Professor Choi’s research team at SNU has identified the Vibrio vulnificus transcription factors at a genome-wide scale and characterized their functions comprehensively, proposing novel targets to control the pathogen.

Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
Prof. Sung Hee Baek
Professor Sunghee Baek's team at SNU identified PHF16 as key to intestinal homeostasis after injury. PHF16 restores the epithelium by activating RAR/RXR target genes via HBO1 histone acetylation and suppressing YAP/TAZ via CDC73 ubiquitination. Its role offers insights for gut repair therapies.