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Research Highlights

Research Highlights /

Research Highlights

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Prof. Dong-Sung Lee

Professor Dongsung Lee from the College of Medicine at SNU, in collaboration with researchers at UCLA and UCSF, has published a paper in Nature, being the first in the world to study epigenomic changes, including the three-dimensional genome structure and DNA methylation, during human brain development from the fetal stage to adulthood at the single-cell level, using the single-nucleus methyl-3C technology they developed.

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Exocyst stimulates multiple steps of exocytic SNARE complex assembly and vesicle fusion

Exocyst stimulates multiple steps of exocytic SNARE complex assembly and vesicle fusion

Prof. Tae-Young Yoon

Exocytosis of secretory vesicles is required for cellular growth, division, and cell-cell communication. Lee et al., reveal that the exocyst tethering complex has stimulatory roles in exocytic SNARE complex assembly and SNARE-mediated vesicle fusion.

Metabolic-methane mitigation by combination of probiotic <i>Escherichia coli</i> strain Nissle 1917 and biochar in rumen fluid <i>in vitro</i> fermentation of dairy cow

Metabolic-methane mitigation by combination of probiotic Escherichia coli strain Nissle 1917 and biochar in rumen fluid in vitro fermentation of dairy cow

Prof. Younghoon Kim

SNU CALS team led by Prof Younghoon Kim demonstrated that combining the probiotic Escherichia coli strain Nissle 1917 with biochar can reduce methane production when applied to rumen fluid and provided insights into the underlying mechanism.

Development of Technology to Predict the Deformation of DNA Origami Structures Induced by DNA-Binding Molecules

Development of Technology to Predict the Deformation of DNA Origami Structures Induced by DNA-Binding Molecules

Prof. Do-Nyun Kim

Recently, research using DNA origami technology to create nanostructures for advanced bio-convergence fields has been actively conducted. Especially, the technology to utilize environmental changes within the body to modify the shape of structures to perform necessary functions is gaining attention.

Professor Byoungyoung Lee's Team at Seoul National University Discovers Security Vulnerability in ARM CPUs Used in Android Smartphones Such as Google Pixel Phones, Increasing Hacking Risks

Professor Byoungyoung Lee's Team at Seoul National University Discovers Security Vulnerability in ARM CPUs Used in Android Smartphones Such as Google Pixel Phones, Increasing Hacking Risks

Prof. Byoungyoung Lee

The College of Engineering at Seoul National University has announced that a research team led by Professor Byoungyoung Lee from the Department of Electrical and Computer Engineering has discovered a security vulnerability in the Memory Tagging Extensions (MTE) feature embedded in CPUs designed by the British semiconductor design company ARM.

The hidden power of shame: how feeling ashamed enhances advertisement recall and positive attitude

The hidden power of shame: how feeling ashamed enhances advertisement recall and positive attitude

Prof. Youjae Yib The Colle

This study investigates the effect of shame on subsequent advertisement processing. Consumers often experience shame in various advertising contexts, such as digital media contexts, TV advertisements, or even daily lives. However, it remains unclear how feeling shame affects consumers’ processing of subsequent advertis...

Energy-saving window for versatile multimode of radiative cooling, energy harvesting, and defrosting functionalities

Energy-saving window for versatile multimode of radiative cooling, energy harvesting, and defrosting functionalities

Prof. Seung Hwan Ko

This study presents an energy-saving window that integrates the multi-mode of radiative cooling, droplet-based electricity generator, and defrosting/defogging functionalities with an all-in-one device architecture.

Development of Biodegradable Electronic Tent for Non-Surgical Brain Disease Diagnosis Using a Needle

Development of Biodegradable Electronic Tent for Non-Surgical Brain Disease Diagnosis Using a Needle

Prof. Seung-Kyun Kang

The College of Engineering at Seoul National University has announced that Professor Seung-kyun Kang’s research team from the Department of Materials Science and Engineering has developed a biodegradable electronic tent technology that enables brain disease diagnosis using a needle.

Professor Yong-Lae Park's Team at Seoul National University Develops The Bilateral Back Extensor Exosuit Revolutionizing Workplace Safety

Professor Yong-Lae Park's Team at Seoul National University Develops The Bilateral Back Extensor Exosuit Revolutionizing Workplace Safety

Prof. Yong-Lae Park

Prof. Yong-Lae Park’s team from the Dept. of Mechanical Engineering has developed the Bilateral Back Extensor Exosuit (BBEX), a cutting-edge robotic back-support device designed to prevent spinal injuries and assist workers in heavy lifting tasks.

Development of Next-Generation Fiber-Based Human-Machine Interface (HMI) Bioelectrodes

Development of Next-Generation Fiber-Based Human-Machine Interface (HMI) Bioelectrodes

Prof. Seung Hwan Ko

The research team validated the strengths of their developed process system and outcomes through various applications, including an in vivo epicardial signal recording ECG electrode, an epidermal electrochemical biosensor, and customized epidermal electromyography (EMG)-based human–machine interface (HMI).

Uremic toxin indoxyl sulfate induces trained immunity via the AhR- dependent arachidonic acid pathway in end-stage renal disease (ESRD)

Uremic toxin indoxyl sulfate induces trained immunity via the AhR- dependent arachidonic acid pathway in end-stage renal disease (ESRD)

Prof. Won-Woo Lee

Professor Won-Woo Lee's team in the Department of Microbiology and Immunology at SNU College of Medicine have identified the mechanism of trained immunity induced by the uremic toxin indoxyl sulfate, suggesting a new therapeutic target for patients with chronic kidney disease.

Molecular basis of facilitated target search and sequence discrimination of TALE homeodomain transcription factor Meis1

Molecular basis of facilitated target search and sequence discrimination of TALE homeodomain transcription factor Meis1

Prof. Juyong Lee

Our study reveals how human transcription factor Meis1 interacts with DNA using NMR and molecular dynamics simulation. Meis1 binds non-specifically its L1-α1 region to the DNA backbone, then achieves specific binding when it finds its target sequence.

Enhancing Ammonia Production by Ag Incorporation in Li-Mediated Nitrogen Reduction Reactions

Enhancing Ammonia Production by Ag Incorporation in Li-Mediated Nitrogen Reduction Reactions

Prof. Yun Jeong Hwang

Professor Yun Jeong Hwang’s research team from Department of Chemistry at SNU improved the performance of electrochemical nitrogen reduction reactions by introducing silver into the electrode. The research identified the silver improves the efficiency of ammonia production and reduces the overpotential of the electrochemical reaction.