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Design of a trigonal halide superionic conductor by regulating cation order-disorder
Prof. Kisuk Kang
Lithium-metal-halides have emerged as a class of solid electrolytes that can deliver superionic conductivity comparable to that of state-of-the-art sulfide electrolytes, as well as electrochemical stability that is suitable for high-voltage (〉4 volt) operations.
Research Highlights Board
Scientists unlock the dog epigenome
Prof. Je-Yoel Cho
Researchers have successfully mapped the dog epigenome and created a high-quality reference map driving new understanding and opening new avenues for functional genomics research in dogs and comparative studies with humans and other species.
Optimized superconductivity in the vicinity of a nematic quantum critical point in the kagome superconductor Cs(V1-xTix)3Sb5
Prof. Kee Hoon Kim
CsV3Sb5 exhibits superconductivity at Tc = 3.2 K after undergoing intriguing two high-temperature transitions: charge density wave order at ~98 K and electronic nematic order at Tnem ~ 35 K.
Targeted degradation of α-synuclein aggregates in Parkinson’s disease using the AUTOTAC technology
Prof. Yong Tae Kwon
There are currently no disease-modifying therapeutics for Parkinson’s disease (PD). Although extensive efforts were undertaken to develop therapeutic approaches to delay the symptoms of PD, untreated α-synuclein (α-syn) aggregates cause cellular toxicity and stimulate further disease progression.
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ
Prof. Ho Jae Han
Lysosomal dysfunction is a pathogenic link that may explain the causal relationship between diabetes and Alzheimer disease; however, there is no information about the regulation of hyperglycemia in neuronal lysophagy modulating lysosomal function.
Ptr1 and ZAR1 immune receptors confer overlapping and distinct bacterial pathogen effector specificities
Prof. Kee Hoon Sohn
Some nucleotide-binding and leucine-rich repeat receptors (NLRs) indirectly detect pathogen effectors by monitoring their host targets.
Harnessing a paper-folding mechanism for reconfigurable DNA origami
Prof. Do-Nyun Kim
Professor Kim Do-Nyun's research team from the Department of Mechanical Engineering at Seoul National University has succeeded in developing DNA nanotechnology, which allows for the folding or unfolding of a single structure into various shapes, harnessing the paper-folding mechanism.
Functional viromic screens uncover regulatory RNA elements
Prof. V. Narry Kim
The number of sequenced viral genomes has surged recently, presenting an opportunity to understand viral diversity and uncover unknown regulatory mechanisms.
Association of antibiotic use with risk of lung cancer: A nationwide cohort study
Prof. Sang Min Park
Although recent studies indicated that antibiotics may be a risk factor for lung cancer, further understanding is needed. We investigated the association of long-term antibiotic exposure with lung cancer risk.
Comparison of the effects of empagliflozin and sotagliflozin on a zebrafish model of diabetic heart failure with reduced ejection fraction
Prof. Seung Hyeok Seok, Prof. Hae-Young Lee
The sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin (EMPA) and dual SGLT1/2 inhibitor sotagliflozin (SOTA) are emerging as heart failure (HF) medications in addition to having glucose-lowering effects in diabetes mellitus (DM).
Drift of Earth’s Pole Confirms Groundwater Depletion as a Significant Contributor to Global Sea Level Rise 1993-2010
Prof. Ki-Weon Seo
Climate model estimates show significant groundwater depletion during the 20th century, consistent with global mean sea level (GMSL) budget analysis. However, prior to the Argo float era, in the early 2000’s, there is little information about steric sea level contributions to GMSL, making the role of groundwater depletion in this period less certain.
Machine learning based estimation of urban on-road CO2 concentration in Seoul
Prof. Sujong Jeong
The urban on-road CO2 emissions will continue to increase, it is therefore essential to manage urban on-road CO2 concentrations for effective urban CO2 mitigation. However, limited observations of on-road CO2 concentrations prevents a full understanding of its variation.
Liquid Metal based Stretchable Room Temperature Soldering Sticker Patch for Stretchable Electronics Integration
Prof. Seung Hwan Ko
Researchers are eagerly developing various stretchable conductors to fabricate devices for next-generation electronics. Most of the major problems in stretchable electronics happen at the connection between rigid and soft parts and the development of reliable soldering material is a major hurdle in stretchable electronics.