Researcher
Researcher
Our lab researches gene regulation mediated by RNA. RNAs are at the core of posttranscriptional regulation, and play pivotal roles in developmental and pathological pathways. We currently work on three major topics (microRNA, RNA tail, and RNA binding proteins) applying biochemical and molecular biological tools, as well as genetic, biophysical, and computational approaches.
Roles of the tumor suppressor BRCA2 in DNA repair and cell cycle control. Regulation of mitosis and the development of chromosome instability in cancer (CIN). Telomere maintenance and cancer susceptibility. Development and analyses of mouse and zebrafish models for CIN type cancer.